|Date of death:||July 4, 2016|
Earth Space Defense
|Played by:||John Storey|
|First appearance:||Independence Day|
|Last appearance:||Independence Day: Resurgence|
Dr. Milton Isaacs was a scientist and physician in charge of Area 51's medical facility.
During the War of 1996, Isaacs was with Okun's side, helping to extract a capture alien from its exoskeleton armor. The alien awoke and killed or harmed everyone in the surgery room, including Isaacs. He later regained consciousness just as the alien was shot by President Whitmore's security detail, but Okun was rendered into a coma.
Since the end of the war, Isaacs spent his time researching new alien technology while also tending the comatose Okun. Twenty years later and on the upcoming anniversary of the war, Isaacs was tending Okun when the latter suddenly woke up.